Biofunctionalization of Microgroove Surfaces with Antibacterial Nanocoatings.

ABSTRACT:

Objectives

To investigate the physical properties of the modified microgroove (MG) and antibacterial nanocoated surfaces. In addition, the biological interactions of the modified surfaces with human gingival fibroblasts (HGFs) and the antibacterial activity of the surfaces against Porphyromonas gingivalis were studied.

Methods

The titanium nitride (TiN) and silver (Ag) coatings were deposited onto the smooth and MG surfaces using magnetron sputtering. A smooth titanium surface (Ti-S) was used as the control. The physicochemical properties including surface morphology, roughness, and hydrophilicity were characterized using scanning electron microscopy, atomic force microscopy, and an optical contact angle analyzer. The "contact guidance" morphology was assessed using c

SUBMITTER: Lai Y 

PROVIDER: S-EPMC7317309 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature