Association of Optical Coherence Tomography Angiography Metrics With Detection of Impaired Macular Microvasculature and Decreased Vision in Amblyopic Eyes: The Hong Kong Children Eye Study.

ABSTRACT:

Importance

Microvascular abnormalities in amblyopia are becoming evident with high-resolution imaging, such as optical coherence tomography angiography (OCT-A); however, to our knowledge, the clinical significance and use of these findings are unknown.

Objective

To assess changes in quantitative OCT-A metrics in amblyopic eyes and explore their association with visual acuity in children.

Design, setting, and participants

This population-based nested case-control study included children aged 6 to 8 years who were consecutively recruited between January 2016 and July 2017 from the population-based Hong Kong Children Eye Study (HKCES) at the Chinese University of Hong Kong Eye Centre. All participants underwent OCT-A with a swept-source OCT and detailed ophthalmic invest

SUBMITTER: Wong ES 

PROVIDER: S-EPMC7317658 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature