Young-onset type 2 diabetes and younger current age: increased susceptibility to retinopathy in contrast to other complications.

ABSTRACT:

Background

Type 2 diabetes diagnosed during youth and early adulthood is aggressive and associated with a high burden of vascular complications. The increase in complications is often attributed to long disease duration and poor metabolic control. Whether people with young-onset type 2 diabetes are inherently more susceptible to long-term complications than those diagnosed in later adulthood is unclear.

Methods

Prospective data from 3322 individuals, diagnosed between the age of 15 and 70 years and collected 10-25 years after diabetes diagnosis, were analysed. The cross-sectional associations between age at diagnosis and microvascular and macrovascular complications were analysed using logistic regression models, adjusted for duration of diabetes exposure and metabolic risk

SUBMITTER: Middleton TL 

PROVIDER: S-EPMC7317898 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature