The status of hepatitis C virus infection among people who inject drugs in the Middle East and North Africa.

ABSTRACT:

Background and aims

People who inject drugs (PWID) are a key population at high risk of hepatitis C virus (HCV) infection. The aim of this study was to delineate the epidemiology of HCV in PWID in the Middle East and North Africa (MENA).

Methods

Syntheses of data were conducted on the standardized and systematically assembled databases of the MENA HCV Epidemiology Synthesis Project, 1989-2018. Random-effects meta-analyses and meta-regressions were performed. Meta-regression variables included country, study site, year of data collection and year of publication [to assess trends in HCV antibody prevalence over time], sample size and sampling methodology. Numbers of chronically infected PWID across MENA were estimated. The Shannon Diversity Index was calculated to assess genot

SUBMITTER: Mahmud S 

PROVIDER: S-EPMC7318323 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature