Transient hyponatremia of prematurity caused by mild Bartter syndrome type II: a case report.

ABSTRACT:

Background

Bartter syndrome subtypes are a group of rare renal tubular diseases characterized by impaired salt reabsorption in the tubule, specifically the thick ascending limb of Henle's loop. Clinically, they are characterized by the association of hypokalemic metabolic alkalosis, hypercalciuria, nephrocalcinosis, increased levels of plasma renin and aldosterone, low blood pressure and vascular resistance to angiotensin II. Bartter syndrome type II is caused by mutations in the renal outer medullary potassium channel (ROMK) gene (KCNJ1), can present in the newborn period and typically requires lifelong therapy.

Case presentation

We describe a case of a prematurely born female infant presenting with antenatal polyhydramnios, and postnatal dehydration and hyponatremia. After

SUBMITTER: Verma S 

PROVIDER: S-EPMC7318402 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature