Cardiac biomarkers of prognostic importance in chronic obstructive pulmonary disease.

ABSTRACT:

Background

Ischemic heart disease is common in COPD and associated with worse prognosis. This study aimed to investigate the presence and prognostic impact of biomarkers of myocardial injury and ischemia among individuals with COPD and normal lung function, respectively.

Methods

In 2002-04, all individuals with airway obstruction (FEV₁/VC < 0.70, n = 993) were identified from population-based cohorts, together with age and sex-matched non-obstructive referents. At re-examination in 2005, spirometry, Minnesota-coded ECG and analyses of high-sensitivity cardiac troponin I (hs-cTnI) were performed in individuals with COPD (n = 601) and those with normal lung function (n = 755). Deaths were recorded until December 31st, 2010.

Results

Hs-cTnI concentrations were

SUBMITTER: Nilsson U 

PROVIDER: S-EPMC7318493 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature