Family history of colorectal cancer and survival: a Swedish population-based study.

ABSTRACT:

Objectives

A family history of colorectal cancer (CRC) is an established risk factor for developing CRC, whilst the impact of family history on prognosis is unclear. The present study assessed the association between family history and prognosis and, based on current evidence, explored whether this association was modified by age at diagnosis.

Methods

Using data from the Swedish Colorectal Cancer Registry (SCRCR) linked with the Multigeneration Register and the National Cancer Register, we identified 31 801 patients with a CRC diagnosed between 2007 and 2016. The SCRCR is a clinically rich database which includes information on the cancer stage, grade, location, treatment, complications and postoperative follow-up.

Results

We estimated excess mortality rate ratios (EM

SUBMITTER: Pesola F 

PROVIDER: S-EPMC7318575 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature