Cardiovascular disease risk and its determinants in people living with HIV across different settings in South Africa.

ABSTRACT:

Objectives

Socio-economic factors and lifestyle are known to differ across geographies and populations, which may result in distinct risk profiles for cardiovascular disease (CVD). This study assessed carotid intima-media thickness (CIMT), a proxy for CVD, and its determinants in two groups of people living with HIV (PLHIV) in two different settings in South Africa.

Methods

A cross-sectional analysis was conducted comparing data from the Ndlovu Cohort Study in the Limpopo Province (group 1) and from three clinical trials in Johannesburg (group 2). The association between demographics, conventional CVD risk factors, HIV-related factors and CIMT in groups 1 and 2 was analysed with two separate multivariable linear regression models.

Results

Group 1 consisted of 826 part

SUBMITTER: Roozen GVT 

PROVIDER: S-EPMC7318654 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature