Incidence of lower extremity amputations among patients with type 1 and type 2 diabetes in the United States from 2010 to 2014.

ABSTRACT:

Aim

To compare the incidence of lower extremity amputation (LEA) among patients with type 1 diabetes (T1D) and patients with type 2 diabetes (T2D) with those without diabetes using US commercial claims and to assess the presence of key co-morbidities and precipitating factors at the time of the LEA.

Methods

Cohorts were defined via IBM MarketScan research databases for beneficiaries with T1D and T2D during 2010-2014. For each T1D and T2D patient, one patient without a prior diabetic claim matched on calendar time, sex and age, was randomly selected. Multivariable Cox proportional hazards models were used to estimate adjusted hazard ratios (aHRs) and 95% confidence intervals.

Results

Among the matched cohorts of 120 129 T1D patients and 1.7 million T2D patients, the in

SUBMITTER: Deruaz-Luyet A 

PROVIDER: S-EPMC7318669 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature