Scintigraphic evaluation of salivary gland function in thyroid cancer patients after radioiodine remnant ablation.

ABSTRACT: Radioiodine (¹³¹ I, RAI) has traditionally been used in thyroid cancer treatment but its benefit should be balanced against possible risks. Among them, salivary gland dysfunction has often been discussed, although the reported data have been inconsistent. The aim of our prospective study was to evaluate salivary gland function in 31 thyroidectomised patients (6 men, 25 women; median age 52 yr) before and 4-6 months after RAI remnant ablation (RRA), using activity of 3.7 GBq ¹³¹ I-NaI. Salivary gland uptake and excretion fractions were quantitatively assessed with ^99m Tc - pertechnetate salivary gland scintigraphy. Pre- and post-treatment values were compared using Wilcoxon signed rank test. No statistically significant difference in the pre- and post-treatm

SUBMITTER: Krcalova E 

PROVIDER: S-EPMC7318700 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature