Development of a structured clinical pharmacology review for specialist support for management of complex polypharmacy in primary care.

ABSTRACT:

Aims

Polypharmacy is widespread and associated with medication-related harms, including adverse drug reactions, medication errors and poor treatment adherence. General practitioners and pharmacists cite limited time and training to perform effective medication reviews for patients with complex polypharmacy, yet no specialist referral mechanism exists. To develop a structured framework for specialist review of primary care patients with complex polypharmacy.

Methods

We developed the clinical pharmacology structured review (CPSR) and stopping by indication tool (SBIT). We tested these in an age-sex stratified sample of 100 people with polypharmacy aged 65-84 years from the Clinical Practice Research Datalink, an anonymised primary care database. Simulated medication reviews ba

SUBMITTER: Threapleton CJD 

PROVIDER: S-EPMC7319011 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature