A publicly available virtual cohort of four-chamber heart meshes for cardiac electro-mechanics simulations.

ABSTRACT: Computational models of the heart are increasingly being used in the development of devices, patient diagnosis and therapy guidance. While software techniques have been developed for simulating single hearts, there remain significant challenges in simulating cohorts of virtual hearts from multiple patients. To facilitate the development of new simulation and model analysis techniques by groups without direct access to medical data, image analysis techniques and meshing tools, we have created the first publicly available virtual cohort of twenty-four four-chamber hearts. Our cohort was built from heart failure patients, age 67±14 years. We segmented four-chamber heart geometries from end-diastolic (ED) CT images and generated linear tetrahedral meshes with an average edge length of 1.1±0.2m

SUBMITTER: Strocchi M 

PROVIDER: S-EPMC7319311 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature