SNPnexus: a web server for functional annotation of human genome sequence variation (2020 update).

ABSTRACT: SNPnexus is a web-based annotation tool for the analysis and interpretation of both known and novel sequencing variations. Since its last release, SNPnexus has received continual updates to expand the range and depth of annotations provided. SNPnexus has undergone a complete overhaul of the underlying infrastructure to accommodate faster computational times. The scope for data annotation has been substantially expanded to enhance biological interpretations of queried variants. This includes the addition of pathway analysis for the identification of enriched biological pathways and molecular processes. We have further expanded the range of user directed annotation fields available for the study of cancer sequencing data. These new additions facilitate investigations into cancer driver varia

SUBMITTER: Oscanoa J 

PROVIDER: S-EPMC7319579 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature