Transfusion Thresholds for Adult Respiratory Extracorporeal Life Support: An Expert Consensus Document.

ABSTRACT: Severe acute respiratory distress syndrome (ARDS) can complicate novel pandemic coronavirus disease (COVID-19). Extracorporeal life support (ECLS) represents the final possible rescue strategy. Variations in practice, combined with a paucity of rigourous guidelines, may complicate blood-product resource availability and allocation during a pandemic. We conducted a literature review around venovenous extracorporeal membrane oxygenation (VV-ECMO) transfusion practices for platelets, packed red blood cells, fresh frozen plasma, prothrombin complex concentrate, and antithrombin. Pertinent society guidelines were examined, and the practice of Canadian ECLS experts was sampled through an environmental scan. This paper represents a synthesis of these explorations, combined with input from the Can

SUBMITTER: Singh G 

PROVIDER: S-EPMC7319637 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature