Cell organelle targeting of near-infrared croconaine dye controls photothermal outcome.

ABSTRACT: Near-infrared croconaine-peptide conjugates that target the cell nucleus promote photothermal induced cell death. In contrast, a croconaine-morpholine conjugate that targets the cell lysosomes promotes lysosome permeabilization without measurable cell phototoxicity.

SUBMITTER: Wen Y 

PROVIDER: S-EPMC7319869 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature