A reactive phase against disruptions for designing a proactive platelet supply network.

ABSTRACT: Previous studies in blood supply chain network design often follow a commonly used approach in protecting the chain against disruptions, considering the effects of disruptions on the designing phase. However, in many real-world situations, disruptions cannot be adequately measured in advance. Moreover, using disruptions in the designing phase through the common two-stage stochastic programming models impose high costs on the network, since they cannot be updated based on unpredicted disruptions. This paper proposes an updatable two-phase approach which deals with disruptions in the operational phase, not in the strategic design phase. In the first step, called the proactive phase, a nominal platelet supply chain network is designed under operational uncertainty, using the whole-bloo

SUBMITTER: Samani MRG 

PROVIDER: S-EPMC7320270 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature