The relationship of prenatal antibiotic exposure and infant antibiotic administration with childhood allergies: a systematic review.

ABSTRACT:

Background

Early antibiotic exposure may be contributing to the onset of childhood allergies. The main objective of this study was to conduct a systematic review on the relationship between early life antibiotic exposure and childhood asthma, eczema and hay fever.

Methods

Pubmed and Embase were searched for studies published between 01-01-2008 and 01-08-2018, examining the effects of (1) prenatal antibiotic exposure and (2) infant antibiotic administration (during the first 2 years of life) on childhood asthma, eczema and hay fever from 0 to 18 years of age. These publications were assessed using the Newcastle Ottawa Scale (NOS) and analysed narratively.

Results

(1) Prenatal antibiotics: Asthma (12 studies): The majority of studies (9/12) reported significant relation

SUBMITTER: Baron R 

PROVIDER: S-EPMC7320596 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature