Corticosteroid administration for viral pneumonia: COVID-19 and beyond.

ABSTRACT:

Background

Corticosteroids are commonly used as adjuvant therapy for acute respiratory distress syndrome by many clinicians because of their perceived anti-inflammatory effects. However, for patients with severe viral pneumonia, the corticosteroid treatment is highly controversial.

Objectives

The purpose of this review is to systematically evaluate the effect and potential mechanism of corticosteroid administration in pandemic viral pneumonia.

Sources

We comprehensively searched all manuscripts on corticosteroid therapy for influenza, severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS) and SARS coronavirus 2 (SARS-CoV-2) viral pneumonia from the PubMed, EMBASE, Web of Science and Cochrane Library databases.

Content

We systematicall

SUBMITTER: Yang JW 

PROVIDER: S-EPMC7320691 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature