Biobased Cryogels from Enzymatically Oxidized Starch: Functionalized Materials as Carriers of Active Molecules.

ABSTRACT: Starch recovered from an agrifood waste, pea pods, was enzymatically modified and used to prepare cryogels applied as drug carriers. The enzymatic modification of starch was performed using the laccase/(2,2,6,6-tetramethylpiperidin-1-yl)oxyl TEMPO system, at a variable molar ratio. The characterization of the ensuing starches by solution NMR spectroscopy showed partial conversion of the primary hydroxyl groups versus aldehyde and carboxyl groups and successive creation of hemiacetal and ester bonds. Enzymatically modified starch after simple freezing and lyophilization process provided stable and compact cryogels with a morphology characterized by irregular pores, as determined by atomic force (AFM) and scanning electron microscopy (SEM). The application of cryogels as carriers of active m

SUBMITTER: Boccia AC 

PROVIDER: S-EPMC7321214 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature