Bioproduction of succinic acid from xylose by engineered Yarrowia lipolytica without pH control.

ABSTRACT:

Background

Xylose is the most prevalent sugar available in hemicellulose fraction of lignocellulosic biomass (LCB) and of great interest for the green economy. Unfortunately, most of the cell factories cannot inherently metabolize xylose as sole carbon source. Yarrowia lipolytica is a non-conventional yeast that produces industrially important metabolites. The yeast is able to metabolize a large variety of substrates including both hydrophilic and hydrophobic carbon sources. However, Y. lipolytica lacks effective metabolic pathway for xylose uptake and only scarce information is available on utilization of xylose. For the economica feasibility of LCB-based biorefineries, effective utilization of both pentose and hexose sugars is obligatory.

Results

In the prese

SUBMITTER: Prabhu AA 

PROVIDER: S-EPMC7321536 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature