Salivary microbiota in periodontal health and disease and their changes following nonsurgical periodontal treatment.

ABSTRACT:

Purpose

The aims of this study were to examine the salivary microbiota in conditions of periodontal health and disease and to explore microbial changes following nonsurgical periodontal treatment.

Methods

Non-stimulated saliva samples were collected from 4 periodontally healthy participants at baseline and from 8 patients with chronic periodontitis at baseline and 3 months following nonsurgical periodontal therapy. The V3 and V4 regions of the 16S rRNA gene from the DNA of saliva samples were amplified and sequenced. The salivary microbial compositions of the healthy participants and patients with periodontitis prior to and following nonsurgical treatment of periodontitis were compared based on the relative abundance of various taxa.

Results

On average, 299 operationa

SUBMITTER: Ko Y 

PROVIDER: S-EPMC7321711 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature