Outcomes of patients with submucosal (T1b) esophageal adenocarcinoma: a multicenter cohort study.

ABSTRACT:

Background and aims

The treatment of submucosal (T1b) esophageal adenocarcinoma (EAC) remains in evolution, with some evidence supporting endoscopic management of low-risk lesions. Using a multicenter cohort, we evaluated outcomes of patients with T1b EAC and predictors of survival.

Methods

Patients diagnosed between 2001 and 2016 with T1b EAC were identified from 3 academic medical centers in the United States. Demographic, clinical, and outcome data were collected. Outcomes studied were overall and cancer-free survival. Cox proportional hazards models were constructed to assess independent predictors of survival.

Results

One hundred forty-one patients were included, of whom 68 (48%) underwent esophagectomy and 73 (52%) were treated endoscopically. Most patients (85.

SUBMITTER: Otaki F 

PROVIDER: S-EPMC7321863 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature