Early Pregnancy Blood Pressure Elevations and Risk for Maternal and Neonatal Morbidity.

ABSTRACT:

Objective

To investigate whether women with early pregnancy elevated blood pressure (BP) or stage 1 hypertension exhibit increased risk of preeclampsia and maternal or neonatal morbidity.

Methods

We conducted a clinical cohort study of 18,162 women who delivered a singleton neonate from 2015 to 2018 and attended at least two prenatal appointments before 20 weeks of gestation. Data were collected within the Magee Obstetric Maternal and Infant database, an aggregate of prenatal and delivery health records. Early pregnancy BP was defined as average BP before 20 weeks of gestation, and women were classified with normal, elevated BP, stage 1 or 2 hypertension according to current guidelines. The primary outcome was preeclampsia. Secondary outcomes were severe maternal morbidity,

SUBMITTER: Sutton EF 

PROVIDER: S-EPMC7321869 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature