Impact of renal function on admission in COVID-19 patients: an analysis of the international HOPE COVID-19 (Health Outcome Predictive Evaluation for COVID 19) Registry.

ABSTRACT:

Background

Coronavirus disease 2019 (COVID-19) is a disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Despite its international aggressive extension, with a significant morbidity and mortality, the impact of renal function on its prognosis is uncertain.

Methods

Analysis from the international HOPE-Registry (NCT04334291). The objective was to evaluate the association between kidney failure severity on admission with the mortality of patients with SARS-CoV-2 infection. Patients were categorized in 3 groups according to the estimated glomerular filtration rate on admission (eGFR > 60 mL/min/1.73 m², eGFR 30-60 mL/min/1.73 m² and eGFR < 30 mL/min/1.73 m²).

Results

758 patients were included: mean age was 66 ± 

SUBMITTER: Uribarri A 

PROVIDER: S-EPMC7322375 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature