Anti-N-methyl-D-aspartate-receptor antibody encephalitis combined with syphilis: A case report.

ABSTRACT:

Background

Anti-N-methyl-D-aspartate-receptor (NMDAR) encephalitis is a common type of autoimmune encephalitis characterized by complex clinical signs and variable imaging manifestations. The pathogenesis of the disease is unclear. Syphilis is an infectious disease caused by Treponema pallidum that can invade the nervous and immune systems and cause systemic symptoms. There are few reports of anti-NMDAR encephalitis with syphilis, and the association between them is unknown; both diseases are related to immune system damage. We report a case of anti-NMDAR encephalitis with syphilis.

Case summary

A 32-year-old man was admitted to our hospital with complaints of cognitive decline, diplopia, and walking instability during the previous 6 mo. He developed dysarthria, diffi

SUBMITTER: Li XY 

PROVIDER: S-EPMC7322422 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature