Risk models for VTE and bleeding in medical inpatients: systematic identification and expert assessment.

ABSTRACT: Risk assessment models (RAMs) for venous thromboembolism (VTE) and bleeding in hospitalized medical patients inform appropriate use of thromboprophylaxis. Our aim was to use a novel approach for selecting risk factors for VTE and bleeding to be included in RAMs. First, we used the results of a systematic review of all candidate factors. Second, we used the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach to assess the certainty of the evidence for the identified factors. Third, we using a structured approach to select factors to develop the RAMs, by building on clinical and methodological expertise. The expert panel made judgments on whether to include, potentially include, or exclude risk factors, according to domains of the GRADE approach and the Delphi

SUBMITTER: Darzi AJ 

PROVIDER: S-EPMC7322970 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature