Vaccine development and therapeutic design for 2019-nCoV/SARS-CoV-2: Challenges and chances.

ABSTRACT: The ongoing outbreak of the recently emerged 2019 novel coronavirus (nCoV), which has seriously threatened global health security, is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with high morbidity and mortality. Despite the burden of the disease worldwide, still, no licensed vaccine or any specific drug against 2019-nCoV is available. Data from several countries show that few repurposed drugs using existing antiviral drugs have not (so far) been satisfactory and more recently were proven to be even highly toxic. These findings underline an urgent need for preventative and therapeutic interventions designed to target specific aspects of 2019-nCoV. Again the major factor in this urgency is that the process of data acquisition by physical experiment is time-consumi

SUBMITTER: Ghaebi M 

PROVIDER: S-EPMC7323389 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature