Bioinformatics Analysis Finds Immune Gene Markers Related to the Prognosis of Bladder Cancer.

ABSTRACT: Bladder cancer is one of the most common malignant tumors of the urinary system that seriously threatens the health of a population. In recent years, the application of immunotherapy has significantly changed the treatment of bladder cancer, but only some patients can benefit from the treatment with immune-checkpoint inhibitors. Many problems are unsolved in the field of bladder cancer immunotherapy, especially in the search for genes that are critical to the level of immune cell infiltration and new effective therapeutic targets. We attempted to use bioinformatics analysis to identify immune gene markers related to the prognosis of bladder cancer and to establish a prognostic signature for bladder cancer patients based on their immune gene expression profiles. We used univariate Cox propo

SUBMITTER: Chen X 

PROVIDER: S-EPMC7324668 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature