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Cotton-Tipped Plastic Swabs for SARS-CoV-2 RT-qPCR Diagnosis to Prevent Supply Shortages.


ABSTRACT: CDC and WHO guidelines for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) diagnosis only recommend synthetic fiber swabs for nasopharyngeal (NP) sampling. We show that cotton-tipped plastic swabs do not inhibit PCR and have equivalent performance to rayon swabs. Cotton-tipped plastic swabs are massively produced worldwide and would prevent swab supply shortages under the current high SARS-CoV-2 testing demands, particularly in developing countries.

SUBMITTER: Freire-Paspuel B 

PROVIDER: S-EPMC7324669 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature

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Cotton-Tipped Plastic Swabs for SARS-CoV-2 RT-qPCR Diagnosis to Prevent Supply Shortages.

Freire-Paspuel Byron B   Vega-Mariño Patricio P   Velez Alberto A   Castillo Paulina P   Gomez-Santos Eliana Elizabeth EE   Cruz Marilyn M   Garcia-Bereguiain Miguel Angel MA  

Frontiers in cellular and infection microbiology 20200623


CDC and WHO guidelines for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) diagnosis only recommend synthetic fiber swabs for nasopharyngeal (NP) sampling. We show that cotton-tipped plastic swabs do not inhibit PCR and have equivalent performance to rayon swabs. Cotton-tipped plastic swabs are massively produced worldwide and would prevent swab supply shortages under the current high SARS-CoV-2 testing demands, particularly in developing countries. ...[more]

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