Automated planning through robust templates and multicriterial optimization for lung VMAT SBRT of lung lesions.

ABSTRACT:

Purpose

To develop and validate a robust template for VMAT SBRT of lung lesions, using the multicriterial optimization (MCO) of a commercial treatment planning system.

Methods

The template was established and refined on 10 lung SBRT patients planned for 55 Gy/5 fr. To improve gradient and conformity a ring structure around the planning target volume (PTV) was set in the list of objectives. Ideal fluence optimization was conducted giving priority to organs at risk (OARs) and using the MCO, which further pushes OARs doses. Segmentation was conducted giving priority to PTV coverage. Two different templates were produced with different degrees of modulation, by setting the Fluence Smoothing parameter to Medium (MFS) and High (HFS). Each template was applied on 20 further patient

SUBMITTER: Marrazzo L 

PROVIDER: S-EPMC7324702 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature