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Systemic Inonotus sp. Infection in a dog.

ABSTRACT: A 3-years-old male golden retriever was presented for decreased activity (lethargy), anorexia, and titubation. Superficial lymph nodes were enlarged, and arrhythmia and tachycardia were auscultated. Fungal hyphae-like structures were detected in the biopsy samples from an enlarged lymph node and spleen. Nucleotide sequence of the internal transcribed spacer region of the fungi amplified by PCR was highly homologous to that of Inonotus pachyphloeus. The dog was treated with antifungal agents such as itraconazole, fluconazole, and voriconazole. Clinical signs resolved for 325 days but the dog died suddenly, possibly because of arrhythmia. Postmortem examination revealed the presence of a disseminated fungal infection. This report describes the case of canine systemic Inonotus sp. infection treated by an antifungal agent.

SUBMITTER: Furusawa Y

PROVIDER: S-EPMC7324816 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature

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Systemic Inonotus sp. Infection in a dog.

Furusawa Yu Y Takahashi Masashi M Iwanaga Tomoko T Yabuki Akira A Kano Rui R Hatai Hitoshi H Sueno Wako W Endo Yasuyuki Y Momoi Yasuyuki Y

The Journal of veterinary medical science 20200504 6

A 3-years-old male golden retriever was presented for decreased activity (lethargy), anorexia, and titubation. Superficial lymph nodes were enlarged, and arrhythmia and tachycardia were auscultated. Fungal hyphae-like structures were detected in the biopsy samples from an enlarged lymph node and spleen. Nucleotide sequence of the internal transcribed spacer region of the fungi amplified by PCR was highly homologous to that of Inonotus pachyphloeus. The dog was treated with antifungal agents such ...[more]

PMID: 32378518

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