Magnetic resonance fingerprinting with quadratic RF phase for measurement of T₂^* simultaneously with δ_f , T₁ , and T₂.

ABSTRACT:

Purpose

This study explores the possibility of using a gradient moment balanced sequence with a quadratically varied RF excitation phase in the magnetic resonance fingerprinting (MRF) framework to quantify T₂^* in addition to δf , T₁ , and T₂ tissue properties.

Methods

The proposed quadratic RF phase-based MRF method (qRF-MRF) combined a varied RF excitation phase with the existing balanced SSFP (bSSFP)-based MRF method to generate signals that were uniquely sensitive to δf , T₁ , T₂ , as well as the distribution width of intravoxel frequency dispersion, Γ . A dictionary, generated through Bloch simulation, containing possible signal evolutions within the physiological range of δf , T₁ , T₂

SUBMITTER: Wang CY 

PROVIDER: S-EPMC7325599 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature