Chromosome Architecture and Gene Content of the Emergent Pathogen Acinetobacter haemolyticus.

ABSTRACT: Acinetobacter haemolyticus is a Gammaproteobacterium that has been involved in serious diseases frequently linked to the nosocomial environment. Most of the strains causing such infections are sensitive to a wide variety of antibiotics, but recent reports indicate that this pathogen is acquiring very efficiently carbapenem-resistance determinants like the blaNDM-1 gene, all over the world. With this work we contribute with a collection set of 31 newly sequenced nosocomial A. haemolyticus isolates. Genome analysis of these sequences and others collected from RefSeq indicates that their chromosomes are organized in 12 syntenic blocks that contain most of the core genome genes. These blocks are separated by hypervariable regions that are rich in unique gene families, but

SUBMITTER: Castro-Jaimes S 

PROVIDER: S-EPMC7326120 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature