Associations between sleep duration and insulin resistance in European children and adolescents considering the mediating role of abdominal obesity.

ABSTRACT:

Background

Short sleep duration has been suggested to lead to insulin resistance both directly by altering glucose metabolism and indirectly through obesity. This study aims to investigate associations between nocturnal sleep duration and insulin resistance considering abdominal obesity as a mediator.

Methods

We analysed data of 3 900 children aged 2-15 years participating in the second (2009/10) and third (2013/14) examination wave of the European IDEFICS/I.Family study (hereafter referred to as baseline and follow-up). Information on nocturnal sleep duration was collected by questionnaires and age-standardised (SLEEP z-score). The homeostasis model assessment (HOMA) was calculated from fasting insulin and fasting glucose obtained from blood samples; waist circumference (WA

SUBMITTER: Thumann BF 

PROVIDER: S-EPMC7326225 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature