Spatial and epidemiological drivers of <i>Plasmodium falciparum</i> malaria among adults in the Democratic Republic of the Congo.

ABSTRACT:

Background

Adults are frequently infected with malaria and may serve as a reservoir for further transmission, yet we know relatively little about risk factors for adult infections. In this study, we assessed malaria risk factors among adults using samples from the nationally representative, cross-sectional 2013-2014 Demographic and Health Survey (DHS) conducted in the Democratic Republic of the Congo (DRC). We further explored differences in risk factors by urbanicity.

Methods

Plasmodium falciparum infection was determined by PCR. Covariates were drawn from the DHS to model individual, community and environmental-level risk factors for infection. Additionally, we used deep sequencing data to estimate the community-level proportions of drug-resistant infections and inc

SUBMITTER: Deutsch-Feldman M 

PROVIDER: S-EPMC7326263 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature