Can dietary self-reports usefully complement blood concentrations for estimation of micronutrient intake and chronic disease associations?

ABSTRACT:

Background

We recently presented associations between serum-based biomarkers of carotenoid and tocopherol intake and chronic disease risk in a Women's Health Initiative (WHI) Measurement Precision subcohort (n = 5488). Questions remain as to whether self-reported dietary data can usefully augment such biomarkers or can be calibrated using biomarkers for reliable disease association estimation in larger WHI cohorts.

Objectives

The aims were to examine the potential of FFQ data to explain intake variation in a WHI Feeding Study and to compare association parameter estimates and their precision from studies based on biomarker-calibrated FFQ intake in larger WHI cohorts, with those previously presented.

Methods

Serum-based intake measures were augmented by using FFQ data

SUBMITTER: Prentice RL 

PROVIDER: S-EPMC7326592 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature