Changes in cross-frequency coupling following closed-loop auditory stimulation in non-rapid eye movement sleep.

ABSTRACT: Regional changes of non-rapid eye movement (NREM) sleep delta and sigma activity, and their temporal coupling have been related to experience-dependent plastic changes during previous wakefulness. These sleep-specific rhythms seem to be important for brain recovery and memory consolidation. Recently, it was demonstrated that by targeting slow waves in a particular region at a specific phase with closed-loop auditory stimulation, it is possible to locally manipulate slow-wave activity and interact with training-induced neuroplastic changes. In our study, we tested whether closed-loop auditory stimulation targeting the up-phase of slow waves might not only interact with the main sleep rhythms but also with their coupling within the circumscribed region. We demonstrate that while closed-loop

SUBMITTER: Krugliakova E 

PROVIDER: S-EPMC7326971 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature