The changing demography of the cystic fibrosis population: forecasting future numbers of adults in the UK.

ABSTRACT: Improvements in management of cystic fibrosis (CF) through specialist centres in the UK have been associated with a step-change in life expectancy. With increasing numbers of adult patients there is a need to review health care provision to ensure it is sufficient to meet future needs. We used UK CF Registry data to project the number of patients aged 16-17 and 18 and older  up to 2030, and numbers therefore requiring specialist adult CF care. Survival modelling was used to estimate age-specific mortality rates. New-diagnosis rates were estimated using diagnoses observed in the Registry and national population figures. Uncertainty in projections was captured through 95% prediction intervals (PI). The number of adults (aged 18 and older) is expected to increase by 28% from 6,225 in 2017 to

SUBMITTER: Keogh RH 

PROVIDER: S-EPMC7327064 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature