Distinguishing risk factors between congenital anophthalmia and microphthalmia using multivariable logistic regression.

ABSTRACT:

Background

Etiologies of congenital microphthalmia and anophthalmia are unclear and commonly thought to be homogenous. To test if risk factors are similar for these two diseases, we compared the risk factors between congenital microphthalmia and anophthalmia in a large Chinese cohort.

Methods

A total of 347 patients with congenital microphthalmia or anophthalmia diagnosed by magnetic resonance imaging (MRI), computed tomography (CT) or ultrasound from 2011 to 2018 were enrolled. Patients' clinical information, used as potential risk factors, was retrospectively collected. A multivariable logistic regression model was used to estimate odds ratios (OR) and 95% confidence intervals (CI).

Results

A total of 347 patients were affected by congenital microphthalmia or anopht

SUBMITTER: Li Y 

PROVIDER: S-EPMC7327332 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature