Altered brain language network in idiopathic peripheral facial paralysis patients with dysarthria.

ABSTRACT:

Background

Dysarthria is one of the common symptoms of facial paralysis (FP). This study aimed to investigate functional alterations in the brain language network in early idiopathic peripheral FP patients with dysarthria using resting-state functional magnetic resonance imaging (fMRI).

Methods

A total of 45 cases of FP (left 22, right 23) and 34 cases of healthy control (HC) were recruited into this study. The data of patients with left-side FP and matched controls (17 cases) were flipped from left to right, and the brain regions were defined as ipsilateral and contralateral regions. The FC of 16 ROIs in classical language centers and regions that may be involved in language function were calculated. After identifying the differences of FC between the two groups, the correl

SUBMITTER: Gao W 

PROVIDER: S-EPMC7327355 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature