Quantitative proteomics reveals rapid divergence in the postmating response of female reproductive tracts among sibling species.

ABSTRACT: Fertility depends, in part, on interactions between male and female reproductive proteins inside the female reproductive tract (FRT) that mediate postmating changes in female behaviour, morphology, and physiology. Coevolution between interacting proteins within species may drive reproductive incompatibilities between species, yet the mechanisms underlying postmating-prezygotic (PMPZ) isolating barriers remain poorly resolved. Here, we used quantitative proteomics in sibling Drosophila species to investigate the molecular composition of the FRT environment and its role in mediating species-specific postmating responses. We found that (i) FRT proteomes in D. simulans and D. mauritiana virgin females express unique combinations of secreted proteins and are enriched for di

SUBMITTER: McCullough EL 

PROVIDER: S-EPMC7329044 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature