Changes in functional connectivity with cognitive behavioral therapy for social anxiety disorder predict outcomes at follow-up.

ABSTRACT: Approximately half of individuals with Social Anxiety Disorder (SAD) treated with psychological intervention do not achieve clinically significant improvement or retain long-term gains. Neurobiological models of SAD propose that disruptions in functioning of amygdala-prefrontal circuitry is implicated in short-term treatment response. However, whether treatment-related changes in functional connectivity predict long-term well-being after psychotherapy is unknown. Patients with SAD completed an incidental emotion regulation task during fMRI before and after treatment with cognitive behavioral therapy or acceptance and commitment therapy (n = 23, collapsed across groups). Psychophysiological interaction analyses using amygdala seed regions were conducted to assess changes in functional conne

SUBMITTER: Sandman CF 

PROVIDER: S-EPMC7329578 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature