Glycemic control and FEV₁ recovery during pulmonary exacerbations in pediatric cystic fibrosis-related diabetes.

ABSTRACT:

Rationale

Whether short-term glucose control in cystic fibrosis-related diabetes (CFRD) is associated with FEV₁ recovery during acute pulmonary exacerbations is unclear.

Methods

Data from all patients with CFRD ages 6-21 years hospitalized in 2010-2016 for pulmonary exacerbations at our CF Center were analyzed, including CFRD status at each encounter, all FEV₁ recorded during each exacerbation, and relevant clinical covariates. Glucose control was analyzed using meter blood glucose area under the curve (AUC) indices. The primary outcome was FEV₁ recovery.

Results

Patients with CFRD who finished IV antibiotics at home were treated for longer than those fully treated in the hospital (22.2 vs. 13.8 days). In those who finished treatment a

SUBMITTER: Okoniewski W 

PROVIDER: S-EPMC7329580 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature