Relationship Between Main Channel Structure of Catalases and the Evolutionary Direction in Cold-Adapted Hydrogen Peroxide-Tolerant Exiguobacteium and Psychrobacter.

ABSTRACT: Catalase has crucial role in adaptive response to H₂O₂. Main channel structure responsible for substrate selectivity was estimated to understand the relationship between the evolutionary direction of catalases from Exiguobacterium oxidotolerans and Psychrobacter piscatorii which survive in cold and high concentration of hydrogen peroxide, and their catalytic property. E. oxidotolerans catalase (EKTA) exhibited a higher ratio of compound I formation rate using peracetic acid (a substrate lager than H₂O₂)/catalase activity using H₂O₂ as the substrate than P. piscatori catalase (PKTA). It was considered that the ratio was attributed to the size of the amino acid residues locating at the

SUBMITTER: Hanaoka Y 

PROVIDER: S-EPMC7329942 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature