Enrollment of Diverse Populations in the INGENIOUS Pharmacogenetics Clinical Trial.

ABSTRACT: Recruitment of diverse populations and subjects living in Medically Underserved Areas and Populations (MUA/P's) into clinical trials is a considerable challenge. Likewise, representation of African-Americans in pharmacogenetic trials is often inadequate, but critical for identifying genetic variation within and between populations. To identify enrollment patterns and variables that predict enrollment in a diverse underserved population, we analyzed data from the INGENIOUS (Indiana GENomics Implementation and Opportunity for the UnderServed), pharmacogenomics implementation clinical trial conducted at a community hospital for underserved subjects (Safety net hospital), and a statewide healthcare system (Academic hospital). We used a logistic regression model to identify patient variables th

SUBMITTER: Shah-Williams E 

PROVIDER: S-EPMC7330082 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature