Sub-solid lung adenocarcinoma in Asian versus Caucasian patients: different biology but similar outcomes.

ABSTRACT:

Background

Asian and Caucasian patients with lung cancer have been compared in several database studies, with conflicting findings regarding survival. However, these studies did not include proportion of ground-glass opacity or mutational status in their analyses. Asian patients commonly develop sub-solid lung adenocarcinomas that harbor EGFR mutations, which have a better prognosis. We hypothesized that among patients undergoing surgery for sub-solid lung adenocarcinomas, Asian patients have better survival compared to Caucasian patients.

Methods

We identified Asian and Caucasian patients who underwent surgical resection for a sub-solid lung adenocarcinoma from 2002 to 2015 at our institution. Sub-solid was defined as ≥10% ground-glass opacity on preoperative CT scan or ≥10

SUBMITTER: Lui NS 

PROVIDER: S-EPMC7330405 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature