Vasoplegia following heart transplantation and left ventricular assist device explant is not associated with inferior outcomes.

ABSTRACT:

Background

Vasoplegia has been associated with inferior outcomes following heart transplantation (HTx). This observational study was designed to investigate outcomes in recipients with vasoplegia following left ventricular assist device (LVAD) explant HTx.

Methods

Patients undergoing LVAD explant followed by HTx from 01/2013-12/2018 at our centre were included. Vasoplegia was defined as the requirement for high dose vasopressor [noradrenaline (>0.5 μg/kg/min) and vasopressin (>1 U/h)] over the first 24 hours following HTx. Demographic and outcome data were retrieved from the transplant unit database.

Results

During the study period 24 patients underwent LVAD explant HTx. Of these, 13 (54.2%) developed vasoplegia. Both groups had similar duration of LVAD support (media

SUBMITTER: Ali JM 

PROVIDER: S-EPMC7330418 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature