Frequency-Specific Resting Connectome in Bipolar Disorder: An MEG Study.

ABSTRACT:

Background

Bipolar disorder (BD) is a serious psychiatric disorder that is associated with a high suicide rate, and for which no clinical biomarker has yet been identified. To address this issue, we investigated the use of magnetoencephalography (MEG) as a new prospective tool. MEG has been used to evaluate frequency-specific connectivity between brain regions; however, no previous study has investigated the frequency-specific resting-state connectome in patients with BD. This resting-state MEG study explored the oscillatory representations of clinical symptoms of BD via graph analysis.

Methods

In this prospective case-control study, 17 patients with BD and 22 healthy controls (HCs) underwent resting-state MEG and evaluations for depressive and manic symptoms. After e

SUBMITTER: Sunaga M 

PROVIDER: S-EPMC7330711 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature