Association of Nonsteroidal Anti-inflammatory Drug Use and Adverse Outcomes Among Patients Hospitalized With Influenza.

ABSTRACT:

Importance

During the ongoing coronavirus disease 2019 pandemic, case reports have suggested that the use of nonsteroidal anti-inflammatory drugs (NSAIDs) may lead to adverse outcomes.

Objective

To study the association of NSAID use with adverse outcomes in patients hospitalized with influenza or influenza pneumonia.

Design, setting, and participants

This cohort study used propensity score matching among 7747 individuals aged 40 years or older who were hospitalized with influenza, confirmed by polymerase chain reaction or antigen testing, between 2010 and 2018. Data were collected using Danish nationwide registers. All analyses reported were performed on May 29, 2020.

Exposures

Prescription fill of an NSAID within 60 days before admission.

Main outcomes and

SUBMITTER: Lund LC 

PROVIDER: S-EPMC7330719 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature