External validation of the European risk assessment tool for chronic cardio-metabolic disorders in a Middle Eastern population.

ABSTRACT:

Background

High burden of chronic cardio-metabolic disorders including type 2 diabetes mellitus (T2DM), chronic kidney disease (CKD), and cardiovascular disease (CVD) have been reported in the Middle East and North Africa region. We aimed to externally validate a non-laboratory risk assessment tool for the prediction of the chronic cardio-metabolic disorders in the Iranian population.

Methods

The predictors included age, body mass index, waist circumference, use of antihypertensive medications, current smoking, and family history of cardiovascular disease and/or diabetes. For external validation of the model in the Tehran lipids and glucose study (TLGS), the Area under the curve (AUC) and the Hosmer-Lemeshow (HL) goodness of fit test were performed for discrimination and cal

SUBMITTER: Asgari S 

PROVIDER: S-EPMC7331242 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature